CEREZYME® is the ONLY ERT (enzyme replacement therapy) that has shown long-term efficacy and safety in multiple studies over 20 years and has been prescribed for over 25 years.

Administration and Dosage:

Therapy with Cerezyme should be directed by physicians knowledgeable in the management of patients with Gaucher disease.

The recommended dosage of Cerezyme based upon disease severity ranges from 2.5 units/kg three times a week to 60 units/kg once every two weeks. For patients weighing 18 kg and greater, infuse the diluted Cerezyme solution over 1 to 2 hours. For patients weighing less than 18 kg, infuse the diluted Cerezyme solution over 2 hours.


Cerezyme® (imiglucerase) for injection is indicated for treatment of adults and pediatric patients 2 years of age and older with Type 1 Gaucher disease that results in one or more of the following conditions:

  • anemia (low red blood cell count)
  • thrombocytopenia (low blood platelet count)
  • bone disease
  • hepatomegaly or splenomegaly (enlarged liver or spleen)

Common Side Effects:

  • Adverse reactions reported in adults include back pain, chills, dizziness,
    fatigue, headache, hypersensitivity reactions, nausea, pyrexia, and
  • Adverse reactions reported in pediatric patients 2 years of age and older are similar to adults.

More information:

Please see full Prescribing Information including Patient Information.


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